Researchers have discovered a gene defect that could lead to the development of a male contraceptive pill. A group of US scientists examining the CATSPER1 gene in Iranian men have found a mutation which controls a protein controlling the movement of sperm.
The CATSPER1 gene has been identified as affecting male fertility and the mutation in question can lead to the protein in question having inhibited or, in some cases, non-existent development which in turn disrupts sperm “hyperactivation”. If this is the case, the sperm lack the speed or energy to enter and fertilise eggs.
According to Dr Allan Pacey (University of Sheffield), it is possible that the gene may “provide a new target for a revolutionary male contraceptive”.
While much work is necessary for this to come to fruition, the concept is sound. Through immunocontraception, the gene is question could be suppressed, implementing temporary infertility in the man in question.
It is also possible that this could lead to a solution for male infertility.
by George Whittle 41734915
BBC Online
Gene defect clue to male pill
Friday, 3 April 2009
http://news.bbc.co.uk/2/hi/health/7979722.stm
