Glowing dogs
Last week the first transgenic dog was produced. The beagle, Ruppy, was cloned with a successful modification of its genome. A gene which was present in sea anemones which made them glow under ultraviolet light was incorporated into a dog fibroblast cell's nucleus, and then the nucleus was inserted into the egg cell of the same species with its nucleus removed. The dog then matured, with all its cells containing this gene.
The incorporated gene coded a protein which was flurecent under ultraviolet light. First, this gene was incorporated into a virus which then was exposed to the cell. Once the gene was injected into nucleus by the virus, this nucleus was taken and inserted into an egg cell.
The point of this was to prove that such cloning and transgenesis can be done in larger mammals and thus can be done in humans to cure diseases and other illnesses.
42055167
for more information go to :
http://www.newscientist.com/article/dn17003-fluorescent-puppy-is-worlds-first-transgenic-dog.html
Last week the first transgenic dog was produced. The beagle, Ruppy, was cloned with a successful modification of its genome. A gene which was present in sea anemones which made them glow under ultraviolet light was incorporated into a dog fibroblast cell's nucleus, and then the nucleus was inserted into the egg cell of the same species with its nucleus removed. The dog then matured, with all its cells containing this gene.
The incorporated gene coded a protein which was flurecent under ultraviolet light. First, this gene was incorporated into a virus which then was exposed to the cell. Once the gene was injected into nucleus by the virus, this nucleus was taken and inserted into an egg cell.
The point of this was to prove that such cloning and transgenesis can be done in larger mammals and thus can be done in humans to cure diseases and other illnesses.
42055167
for more information go to :
http://www.newscientist.com/article/dn17003-fluorescent-puppy-is-worlds-first-transgenic-dog.html
