Research was performed using a lab mouse model in which the gene was 'knocked out' thus its protein was missing. This produced teeth with no enamel coating. With this research it may be possible to use teeth stem cells for the stimulation of production of new enamel
[A normal mouse tooth (Left) where the cells that produce enamel are glowing red. A mouse tooth without the Ctip2 gene (Right) shows lower levels of enamel produced.]
Link to article:
http://www.sciencedaily.com/releases/2009/02/090223221345.htm
By Calum Thwaites (42059521)