One protein mediates damage from high-fructose diet

High fructose diets can cause a number of serious disorders with the metabolic system, these metabolic disorders include , fatty liver disease and insulin resistance, which has been related to type 2 diabetes.

I have found an article stating that these disease are only present within a person with a high fructose diet when a certain protein within the liver is also present. This protein is called PGC-1 beta . studies on mice with a high fructose diet have shown that by knocking out or removing this protein found in the liver , can prevent or even reverse some of the damage that is associated with a high fructose diet. But there is a problem getting rid of PGC-1 beta in mice that ate a regular diet actually caused insulin resistance. The researchers believe that this discovery will eventually lead to the prevention of insulin resistance.

The article can be found at http://www.sciencenews.org/view/generic/id/41381/title/One_protein_mediates_damage_from_high-fructose_diet

Dan Mumford
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