After decades of research, sciencetists may finally be honing in on specific genes tied to all types of addictions - and finding that some of the same genes associated with alcohol dependence are also closely linked with addictions to nicotine, cocaine, opoids, heroin and other substances.
New insights and signficant progress into understanding the genetics of addiction has been made over the last couple years and this is to be presented in a paper written by addiction experts at the University of Virginia and the University of Michigan.
Researchers have linked several genes to mulitple addictions. Ming Li, Ph.D., professor of psychiatry and neurobehavioral sciences at the UVA School of Medicine states that 'Once researchers can pinpoint exact genetic variants and molecular mechanisms, then we can create much more effective, even personalized, treatments for individuals addicted to a variety of substances." (Ming Li, 2009)
The report also presents a summary of specific genomic locations on 11 chromosomes where addictions to alcohol, cannabis, cocaine, heroin, nicotine and opoids are clustered together. Future research will be focusing on specific gene clusters and also expanding and using additional samples from other ethnic groups.
Figure 1. is a summary of chromosomal locations of peaks or intervals for addictions to a range of substances.
References:
University of Virginia Health System (2009, March 16). Common Genes Tied To Alcohol, Nicotine, Cocaine Addictions. ScienceDaily. Retrieved March 26, 2009, from http://www.sciencedaily.com /releases/2009/03/090310142912.htm
s42059763
