Common genes tied to addictions

For many years the reason behind why people get addicted to substances such as alcohol, cocaine, heroin and other substances has baffled the scientific community. However researches may finally be getting closer to the reason behind addictions. In the April 2009 issue of ‘Nature reviews genetics’ addiction experts present new advancements into the significance of genes behind addictions to many narcotics. "Addiction researchers have found that several genes are linked to multiple addictions. Once researchers can pinpoint exact genetic variants and molecular mechanisms, then we can create much more effective, even personalized, treatments for individuals addicted to a variety of substances," (Ming and Burmeister, 2009).

This article presents specific genomic locations on 11 different chromosomes where alcohol, cocaine, heroin and other narcotic addictions are clustered together. "The comparison of peaks for addictions to multiple substances on certain chromosomal locations confirms that genetic vulnerability to different substances overlaps, in part," (Ming and Burmeister, 2009). This information would prove extremely useful in the rehabilitation of people who have severe addictions to any of the narcotics mentioned. The exact nature of these gene variants is still unknown however further research into the specific genes which cause addiction may soon be able to save many lives.




The above image displays the 11 chromosomes, and the corresponding genes, which have been linked to addiction of multiple narcotics.

Journal reference:
1. Ming D. Li & Burmeister. M, New insights into the genetics of addiction [online], Available from URL: http://www.sciencedaily.com/releases/2009/03/090310142912.htm (Accessed 30-3-09)