27 April 2009

Genetic Discovery Could Lead To Advances In Dental Treatment

Recent genetic research has identified the gene that is responsible for control of the production of tooth enamel. This new research could lead to restoration and even production of teeth for the human body. This gene, Ctip2 is a transcription factor that has several functions that are already known.

Research was performed using a lab mouse model in which the gene was 'knocked out' thus its protein was missing. This produced teeth with no enamel coating. With this research it may be possible to use teeth stem cells for the stimulation of production of new enamel.

[A normal mouse tooth (Left) where the cells that produce enamel are glowing red. A mouse tooth without the Ctip2 gene (Right) shows lower levels of enamel produced.]






Link to article:
http://www.sciencedaily.com/releases/2009/02/090223221345.htm

By Calum Thwaites (42059521)