13 May 2009

Genetic Variation between Races the Key to Disease-related Genes?


Mexican scientists have completed a study which analysed the genetic compositions of Mexican populations in comparison to the three other known human genetic subgroups; African, Caucasian and Asian. The scientists found that there were substantial differences between the genetic makeup of Mexicans and other races.

Scientists believe that by comparing the genetic compositions of different racial groups, they will be able to better understand disease-related genes and will be able to develop medicines which are more tailored to specific genetic groups.

The recent outbreak of H1N1 Influenza A (Swine Flu), for example, demonstrated the potential correlation between race and disease because whilst cases of the flu were reported in many different countries, fatalities from the disease occurred almost exclusively in Mexico. By studying genomic variability between races, it might be possible to identify the genetics variations which make people more susceptible to diseases. Already a genetic characteristic in Asians has been identified which confers for a susceptibility to Hepatitis B.

This new information concerning Mexican genetic compositions will add to the database of knowledge that already exists concerning the genetic variability between races. With continuing research into this area, scientists hope to identify more health-related genes which will significantly affect the knowledge, diagnosis, prevention and treatment of diseases and disorders in the future.

Reference:
National Institute of Genomic Medicine, Mexico. "Landmark Study Reveals Significant Genetic Variation Between Mexico's Population And World's Other Known Genetic Subgroups." ScienceDaily 12 May 2009. 13 May 2009 .