18 March 2009

Genes, Environment and Bad Behavior

Some scientists believe that behavioral problems and susceptibility to behavioral problems can be partially determined by our genetic makeup. Isolating behavioral patterns believed to be hereditary has dated back to the 1800’s with the basic descriptions of Sir Francis Galton. In modern science with the discovery of DNA, behavioral patterns in people can be predicted to an extent (dependant on the environment).



A study directed by Avshalom Caspi proved to find a correlation between genetic makeup, environment and behavioral patterns in a large birth cohort in New Zealand. In this birth cohort he analyzed a polymorphism in a gene responsible for the production of the enzyme monoamine oxide. This enzyme is used to break down serotonin, dopamine and epinephrine for neurotransmitters and has been found to be responsible for aggressive behaviors in rodents. Initially, the gene itself couldn’t be found to cause antisocial behavior; part of trigger for the associated behavior was due to the environment. This was seen as 85% of males with the gene and an unfavorable environment had been profiled with aggressive behavioral problems by the age of 26. It is in this way that Caspi found a correlation between genetic makeup, environment and behavioral patterns.



References:
Rethinking Behavior Genetics - Dean Hamer, 2000 - http://www.sciencemag.org/cgi/content/full/298/5591/71