Type 2 diabetes is characterized by high blood glucose due to insulin resistance and relative insulin deficiency. The discovery by diabetes UK on variation in gene CYP2C9 may provide better effective treatment for the disease. The person with the variant in the gene s is three times more likely to have good glucose level in the blood when taking with diabetes drug. The study is done by looking at 1,073 people with Type 2 diabetes who had been treated with sulphonylureas . The results show that six people in every 100 people with two variants of the gene CYP2C9 were 3.4 times more likely to achieve good glucose level range. The variation in the gene can reduce the effectiveness of the gene to produce enzyme that can break down sulphonylureas in the liver. Hence the treatment can be tailored for person according to their genetic makeup. This will reduce the cost that is used for ineffective drug treatment. All in all, this new discovery can lead to effective treatment for type 2 diabetes.
Source: http://www.medicalnewstoday.com/articles/166669.php
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